On September 22, 2022, authorities raided the home of Hamedi and arrested her in relation to her reporting on the hospitalization and death of Mahsa Amini. Hamedi was one of the first journalists to cover Amini's story and published a photo of her parents hugging in the hospital that spread rapidly online. Hamedi has been subjected to prolonged solitary confinement. On October 28, 2022, the Iranian Ministry of Intelligence and the intelligence agency of the Islamic Revolutionary Guard accused Hamedi and another journalist of planning to orchestrate nationwide protests with their reporting as agents of foreign intelligence agencies. In November 2022, a government official revealed that Hamedi had been charged with "colluding with the intention of acting against national security and propaganda against the state."